CORDIS Project
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The project focuses on developing a new class of fluorescent biosensors using nanobodies to monitor cellular processes. By eliminating the need for blocking peptides, this technology aims to enhance our understanding of protein activity and facilitate drug development.
The development of genetically-encoded fluorescence sensors revolutionized the monitoring of biochemical processes in living cell by reporting a change in their fluorescence properties in response to a specific aspect of their environment.
However, the design of such biosensors is not trivial and available tools only target a limited set of phenomena.
Current limitations prevent the monitoring of crucial processes such as the activity of membrane associated receptors which are a rich target for…
KATHOLIEKE UNIVERSITEIT LEUVEN
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