CORDIS Project
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This research investigates how the long non-coding RNA COOLAIR regulates the flowering time in Arabidopsis thaliana by silencing the FLC gene in response to cold temperatures. It aims to elucidate the molecular mechanisms behind this epigenetic regulation.
In the model plant Arabidopsis thaliana, the integration of complex developmental and environmental cues to determine flowering time occurs via tight regulation of FLC.
During winter, prolonged cold quantitatively down-regulates FLC expression at the whole-plant level, acting via a cell-autonomous epigenetic switch. A long non-coding RNA, COOLAIR, is transcribed antisense to FLC and plays a key role in this switch. COOLAIR knockout lines show slower silencing of FLC in the cold and altered chrom…
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