CORDIS Project
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This research aims to uncover how the human cytomegalovirus alters host cell gene expression to facilitate its replication. By employing advanced sequencing and imaging techniques, it seeks to understand both posttranscriptional regulation and changes during the virus's latent phase.
The herpesvirus human cytomegalovirus (HCMV) infects the majority of the world's population, leading to severe diseases in millions of newborns and immunocompromised adults annually.
During infection, HCMV extensively manipulates cellular gene expression to maintain conditions favorable for efficient viral propagation.
Identifying the pathways that the virus relies on or subverts is of great interest as they have the potential to provide new therapeutic windows and reveal novel principles in cel…
WEIZMANN INSTITUTE OF SCIENCE
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