CORDIS Project
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The UPGRADE project investigates the potential of using gonadotropin-releasing hormone (GnRH) therapy to improve cognitive function in patients with Alzheimer’s disease. By restoring GnRH levels through pulsatile administration, the project aims to enhance cognitive performance and quality of life for individuals affec…
Cognitive decline associated with Alzheimer disease (AD) and other age-related dementias affects ~55 million people worldwide, and is a growing problem in aging European societies.
However, most drugs fail at clinical trial, and approved treatments aimed at controlling or reversing pathological changes in the brain do not improve cognition in patients, besides having significant side effects.
It is thus essential to design and test alternative approaches to enhance cognitive performance and redu…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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