CORDIS Project
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This research focuses on understanding the molecular pathways that regulate plasma cells, which are crucial for immune responses. By using advanced techniques to analyze gene expression changes, the project aims to uncover insights relevant to autoimmune diseases and cancer treatment.
Plasma cells (PCs) are antibody-producing cells that develop from activated B cells in an immune response.
Antibodies produced by these cells are essential for the clearance of pathogens and long-term protection against recurrent infections. PCs can also be pathogenic in autoimmune disease, where self-recognising antibodies are produced, and cancer, in the form of multiple myeloma.
An understanding of the molecular pathways that control PC function is therefore necessary for understanding human…
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