CORDIS Project
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This project aims to develop a new class of drugs that inhibit vascular endothelial growth factor (VEGF) to combat excessive blood vessel formation associated with cancer and eye diseases. By employing an innovative screening method, the project seeks to enhance therapeutic efficacy while minimizing side effects, ultim…
Angiogenesis is the mechanism of blood vessel formation from pre-existing ones and is vital for nutrient and oxygen delivery to all cells in the organism.
However, dysregulation of angiogenesis is detrimental for the organism.
Excessive or abnormal angiogenesis is a hallmark of cancer and various retinopathies and favours tumour growth and metastasis, and vision loss, respectively.
Excessive or abnormal angiogenesis is fuelled by hypoxia-driven expression of high levels of vascular endothelial g…
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
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