CORDIS Project
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The VesselCVO project investigates the cellular and molecular structure of the circumventricular organs in the brain, focusing on their unique blood vessels that facilitate communication between the brain and peripheral organs. It aims to understand how these structures function in health and are affected by diseases l…
In the brain, the blood vasculature harbours a unique specification: the Blood Brain Barrier (BBB), which restricts blood/brain exchanges to a select set of molecules.
This particularity makes neurons blind to most peripheral signal.
However, the peripheral organs and the brain have to communicate to maintain homeostasis and body functions such as metabolism, reproduction or growth.
This dialog occurs in specific brain regions, the circumventricular organs (CVOs), characterized by a fenestrated…
UPPSALA UNIVERSITET
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