CORDIS Project
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This project develops advanced imaging technology to study early infection processes of negative-sense RNA viruses, focusing on respiratory syncytial virus. It aims to uncover how viral replication and transcription are coordinated, the causes of infection variability, and the implications for disease outcomes.
Viruses are simple replicative units built from two components: a nucleic acid and a small number of associated proteins.
Upon entering a cell, viruses co-opt the hosts machineries to copy their genetic material, while shutting down the hosts antiviral immune response.
The success of viral infection differs dramatically from cell to cell through poorly understood mechanisms, resulting in heterogenous propagation through tissues, and ultimately, heterogeneous disease progression.Although viruses…
KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
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