CORDIS Project
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This project aims to explore the role of mechanical cues in the directional migration of Neural Crest cells. It seeks to understand how these cells interact with their environment and how this affects their movement in living organisms.
Directional cell migration is important in physiology and pathology.
Molecular mechanisms regulating directional migration are largely studied; but the role of mechanical cues and their interplay with biochemical signals during directional migration is poorly understood.
To address this we will use Neural Crest (NC) cells, a highly migratory embryonic cell population.
Evidence about how chemical cues regulate NC migration has accumulated, but nothing is known about the biomechanics of NC migrati…
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