CORDIS Project
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The WaddingtonMemory project investigates how certain proteins influence cell fate changes without DNA mutations. By studying these mechanisms in fruit flies and mammalian cells, it aims to uncover the role of epigenetic factors in cancer and development, offering insights into cellular transformation processes.
Epigenetics, the study of molecules and mechanisms that perpetuate alternative gene activity states in the context of the same DNA sequence, is an exciting field with important epistemological and biomedical implications, but the molecular mechanisms underlying epigenetic inheritance are still little understood.
Polycomb group proteins are pleiotropic chromatin components that have been suggested to be capable of driving epigenetic inheritance and their dysregulation leads to cell fate changes a…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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