CORDIS Project
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This project investigates the role of Wolbachia bacteria in providing antiviral protection to hosts, particularly in the context of diseases like dengue and Zika. It aims to understand the genetic interactions between Wolbachia and its host to develop potential applications in disease control.
Wolbachia are arguably the most prevalent intracellular bacteria in animals, infecting filarial nematodes and up to 66% of arthropod species.
Wolbachia are maternally transmitted and can induce a large range of strong phenotypes on their hosts.
However, very little is known on how they induce these phenotypes and how they interact with the host at the molecular level.
One main difficulty with this system is that Wolbachia have been genetically intractable.
We will study how Wolbachia confers pro…
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