CORDIS Project
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This research focuses on how animals regulate oxygen levels and respond to hypoxia using the nematode C. elegans as a model. It aims to uncover molecular mechanisms involved in oxygen sensing and the physiological adaptations to varying oxygen conditions.
Oxygen (O2) is vital for the life of all aerobic animals.
However, fine-tuned regulation of O2 levels is crucial since both shortage (hypoxia) and excess (via the production of reactive oxygen species, ROS) may be harmful.
Indeed, both hypoxia and ROS may underlie the pathophysiology of many diseases such as atherosclerosis and Alzheimer’s.
To understand how this fine-tuned O2 regulation is achieved at both the molecular and organismal levels my research proposal aims to explore the following in…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
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