CORDIS Project
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This project aims to understand the role of autophagy in cellular defense against microbial pathogens. It seeks to elucidate how pathogens evade autophagic responses and the molecular mechanisms involved in recognizing and degrading these pathogens, contributing to the fields of cell biology and infection.
Autophagy is an essential process that enables cells to engulf and digest portions of their cytoplasm, thereby accomplishing quality and quantity control of organelles, proteins and pathogens.
These homeostatic and adaptive function intricately link autophagy to diverse health and disease states including innate immunity.
Microbial pathogens that successfully parasitize eukaryotic cells have evolved to evade autophagic microbial defenses (xenophagy) and subvert the host autophagic responses for…
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
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