CORDIS Project
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The XB-LIVAT project investigates the complex interactions between liver and visceral fat tissues to understand the progression of metabolic dysfunction-associated liver disease. Utilizing advanced three-dimensional cell culture models, the project aims to identify molecular mechanisms and potential therapeutic targets…
With the obesity epidemic and prevalence of 25%, metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent liver disease in the world.
Despite the enormous economic and clinical burden that MASLD poses, there are still no approved therapies.
Mechanisms regulating disease progression are largely unknown, but the crosstalk of liver and visceral adipose tissue (VAT) in the context of obesity, appears to be instrumental in driving the onset of steatosis and progression t…
FONDAZIONE ITALIANA FEGATO ONLUS
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