CORDIS Project
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YOUNGatHEART investigates how non-inherited epigenetic changes contribute to dilated cardiomyopathy and heart failure. The project aims to understand cardiac aging and explore potential therapeutic interventions through epigenetic remodeling.
Aging poses the largest risk for cardiovascular disease (CVD) and is orchestrated, to some extent, by epigenetic changes.
Despite the significant progress on many fronts in the cardiovascular field, non-inherited epigenetic regulation in cardiac aging and CVD remains unexplored.
Dilated Cardiomyopathy (DCM) is a major contributor to healthcare costs and it is the leading indication for heart transplantation.
We have recently discovered that adult cardiac-specific deletion of epigenetic regulator…
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
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