CORDIS Project
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This project focuses on stabilizing metabotropic glutamate receptors using specially designed polymers to enhance drug discovery for neurological disorders. By mimicking the natural lipid environment, the project aims to improve the structural integrity of these receptors, facilitating better understanding of protein-d…
Membrane proteins, particularly G-protein-coupled receptors (GPCRs), represent 25-30% of current drug targets.
Among them, metabotropic glutamate receptor (mGluR), a Class C and group 1 type GPCR, is emerging as an attractive therapeutic target for various neurological and psychiatric disorders such as Alzheimer’s disease, Parkinson's disease, autism spectrum disorder, schizophrenia, and neuropathic pain.
Despite the availability of its complete structure, biophysical characterization and drug d…
FYZIKALNI USTAV AV CR V.V.I
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Taiwan, Taoyuan City
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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