CORDIS Project
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This research explores the role of zyxin, a protein found in cell adhesion structures, in cellular signaling and gene regulation. By combining cell biology and advanced biophysical techniques, the project aims to understand how zyxin influences cell behavior and communication.
Cell adhesion to the extracellular matrix (ECM) is essential to the normal functioning of many tissues.
At the cellular level, adhesion to ECM regulates a host of activities including cell migration, proliferation and death. A feature of many disease is that cell adhesion to the ECM is perturbed in such a way that control of normal cell function is lost.
Cell adhesion to the ECM is mediated primarily through a group of transmembrane receptors (integrins) that cluster into complex, multi-protein…
THE UNIVERSITY OF BIRMINGHAM
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