CORDIS Project
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This project investigates cancer-associated cachexia, a syndrome affecting cancer patients, particularly those with pancreatic cancer. It aims to identify metabolic changes that can predict cachexia and develop therapeutic strategies to alleviate its effects.
Cancer-associated cachexia (CAC) is a multifactorial syndrome causing significant morbidity and mortality in cancer patients and indicates a poor prognosis.
Nearly 80% of cancer patients experience CAC, which directly accounts for almost 20% of all cancer deaths, mainly in patients with pancreatic adenocarcinoma (PDAC).
Clinically, CAC manifests as weight loss and wasting of skeletal muscle mass.
Thus, CAC patients experience reduced physical, emotional, and social well-being, leading to increas…
WEIZMANN INSTITUTE OF SCIENCE
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