CORDIS Project
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This project aims to develop off-the-shelf regulatory T cell products for treating autoimmune diseases and organ transplant rejection. By utilizing human induced pluripotent stem cells and a novel epigenetic editing method, it seeks to create universally applicable Treg therapies without the need for patient-specific c…
Regulatory T cells (Treg) are a type of immune cell that can suppress harmful inflammation caused by autoimmune diseases or organ transplant rejection.
Using Treg as a living drug is a promising form of precision medicine, but it faces many practical and economic challenges, such as the need to produce a specific cell product for each patient. A more feasible solution would be to create off-the-shelf Treg products that are readily available and can be used universally without customizing them fo…
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