CORDIS Project
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This project investigates the role of platelets in unruptured intracranial aneurysms (IAs) and aims to develop a pharmacological treatment to prevent their rupture. By targeting a specific platelet receptor, it seeks to establish a new therapeutic approach to reduce the risk of subarachnoid hemorrhage.
In the European Union, an estimated 15 million individuals harbour unruptured intracranial aneurysms (IAs), each at constant risk of rupture and subsequent subarachnoid haemorrhage (SAH).
The imminent threat of IA rupture remains a significant clinical challenge, further exacerbated by the absence of safe and efficacious non-invasive treatments, mainly due to gaps in understanding the underlying mechanisms.
Notably, intrasaccular clot formation is a prevalent feature of both ruptured and unruptu…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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