CORDIS Project
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This project aims to commercialize single-cell metabolomics technology to enhance drug development by monitoring off-target effects at the cellular level. It seeks to provide insights into drug toxicity, potentially improving the safety and efficacy of new drug candidates.
Despite the major efforts in the modern drug discovery and development, the field is still in its crisis with the productivity increasingly declining. A major source of drug development failure is the toxicity where the adverse drug reaction is often caused by off-target effects of drug candidates that can be revealed only late in the drug development process.
Metabolomics was proposed as an emerging promising approach to monitor off-targets effects on metabolic enzymes or transporters thus prov…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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