CORDIS Project
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This project focuses on developing a novel diagnostic method for cancer detection using histone post-translational modifications in cell-free DNA from blood plasma. It aims to create a cost-effective and sensitive approach for early cancer diagnosis and monitoring, surpassing current techniques based on DNA mutations a…
Over recent years, cancer diagnostics based on cell-free DNA (cfDNA) in liquid biopsies demonstrated great promise in guiding treatment and screening for recurrent diseases.
Current diagnostic strategies are mainly based on the analyses of DNA mutations, fragment length or DNA methylation status.
However, these strategies do not provide a universal approach for cancer identification, are costly and labour intensive, and generally fall short in detecting cancer at early tumorigenic stages or mini…
KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
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