CORDIS Project
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This project focuses on enhancing the effectiveness of peptide-based vaccines by improving the intracellular processing of antigenic peptides for better presentation on immune cells. The goal is to boost the activation of T cells that recognize pathogens or cancer cells, potentially leading to more effective vaccines.
Peptides have great potential for vaccines.
Peptide-based vaccines aim to increase the population and activity of pathogen/cancer-recognizing T cells by administering antigenic peptides carrying epitopes for major histocompatibility (MHC) class I and II.
These peptides are endocytosed by dendritic cells (DCs), followed by intracellular proteolytic processing to release the epitopes, the loading of the epitopes on MHC, and finally the presentation to antigen-specific T cells.
Despite numerous stu…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
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Guests see up to 5 EuroSciVoc fields.
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