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The POPCORN project aims to develop a novel oncolytic virus platform that expresses immunomodulatory antibodies to target aggressive pediatric brain tumors, specifically Diffuse Midline Gliomas. By enhancing the immune response against these tumors, the project seeks to improve treatment outcomes and survival rates for…
Diffuse Midline Gliomas (DMGs) are the most aggressive pediatric brain tumors in desperate need of curative treatment.
The median life expectancy of these children remains below 14 months after diagnosis, and nearly none survive beyond the second year.
Similarly, for other high-risk pediatric brain tumors, there is hardly any option after recurrence, and long-term survivors are faced with life-long sequelae that impact their quality of life.
In this scenario, there is an urgent need for innovati…
UNIVERSIDAD DE NAVARRA
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